Marc W Nolte Selected Research

Factor XIIa (Coagulation Factor XIIa)

1/2022	Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.
1/2017	Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa.
1/2016	FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis.
1/2016	Targeting coagulation factor XII as a novel therapeutic option in brain trauma.
1/2016	The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats.
11/2012	Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway.

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Marc W Nolte Research Topics

Disease

4	Thrombosis (Thrombus) 11/2021 - 02/2014
4	Inflammation (Inflammations) 01/2017 - 11/2012
3	Ischemia 12/2018 - 01/2013
3	Alzheimer Disease (Alzheimer's Disease) 01/2016 - 08/2010
3	Hemorrhage 01/2016 - 02/2014
2	Atherosclerosis 01/2022 - 01/2017
2	Hemophilia B (Haemophilia B) 12/2020 - 05/2014
2	Pathologic Processes 01/2017 - 01/2013
2	Brain Ischemia (Cerebral Ischemia) 01/2016 - 11/2012
2	Stroke (Strokes) 01/2016 - 09/2012
2	Reperfusion Injury 01/2016 - 01/2013
2	Wounds and Injuries (Trauma) 01/2016 - 02/2014
2	Infarction (Infarctions) 05/2013 - 11/2012
1	Pathologic Constriction (Stenosis) 01/2022
1	Abdominal Aortic Aneurysm 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Atherosclerotic Plaque (Atheroma) 01/2022
1	Brain Edema (Cerebral Edema) 01/2017
1	Lung Injury 01/2017
1	Necrosis 01/2017
1	Brain Injuries (Brain Injury) 01/2017
1	Thrombasthenia (Glanzmann Thrombasthenia) 04/2016
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2016
1	Neuroinflammatory Diseases 01/2016
1	Hereditary Angioedema Type III 08/2015
1	Edema (Dropsy) 08/2015
1	Neuroblastoma 01/2013
1	AIDS-Related Complex (ARC) 03/2011
1	Seizures (Absence Seizure) 09/2008
1	Drug Resistant Epilepsy 09/2008

Drug/Important Bio-Agent (IBA)

8	Factor XII (Hageman Factor)IBA 11/2021 - 02/2014
6	Factor XIIa (Coagulation Factor XIIa)IBA 01/2022 - 11/2012
3	Apolipoproteins E (ApoE)IBA 01/2022 - 05/2013
3	Proteins (Proteins, Gene)FDA Link 12/2020 - 03/2011
2	Factor IX (Coagulation Factor IX)FDA LinkGeneric 12/2020 - 05/2014
2	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 01/2017 - 01/2013
2	ApolipoproteinsIBA 01/2017 - 05/2013
2	BradykininIBA 01/2017 - 08/2015
2	KininsIBA 01/2017 - 09/2012
2	TransglutaminasesIBA 04/2016 - 05/2013
2	FibrinIBA 04/2016 - 02/2014
2	Amyloid (Amyloid Fibrils)IBA 01/2016 - 03/2011
2	Intravenous Immunoglobulins (IVIG)FDA Link 01/2016 - 01/2013
2	Peptide Hydrolases (Proteases)FDA Link 08/2015 - 02/2014
2	Neutralizing AntibodiesIBA 08/2015 - 02/2014
2	Peroxidase (Myeloperoxidase)IBA 05/2013 - 11/2012
2	Factor XIII (Coagulation Factor XIII)IBA 05/2013 - 11/2012
1	Angiotensin IIIBA 01/2022
1	Monoclonal AntibodiesIBA 01/2022
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2017
1	CC ChemokinesIBA 01/2017
1	EnzymesIBA 01/2017
1	Interleukin-12 (IL 12)IBA 01/2017
1	CytokinesIBA 01/2017
1	Histones (Histone)IBA 01/2017
1	ImmunosorbentsIBA 01/2017
1	LigandsIBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	AntibodiesIBA 01/2016
1	Human Serum Albumin FDA LinkGeneric 01/2016
1	Immunoglobulin G (IgG)IBA 01/2016
1	Therapeutic UsesIBA 01/2016
1	Fibrinogen (Factor I)FDA Link 10/2014
1	Recombinant Fusion ProteinsIBA 05/2014
1	AlbuminsIBA 05/2014
1	AnticoagulantsIBA 02/2014
1	Heparin (Liquaemin)FDA LinkGeneric 02/2014
1	Hemostatics (Antihemorrhagics)IBA 02/2014
1	A-factor (Streptomyces)IBA 02/2014
1	Chemokine ReceptorsIBA 05/2013
1	Small Interfering RNA (siRNA)IBA 05/2013
1	Complement Receptors (Complement Receptor)IBA 01/2013
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 03/2011
1	Peptides (Polypeptides)IBA 08/2010
1	Amyloid beta-PeptidesIBA 08/2010
1	gamma-Aminobutyric Acid (GABA)IBA 09/2008
1	Anticonvulsants (Antiepileptic Drugs)IBA 09/2008

Therapy/Procedure

3	Therapeutics 02/2014 - 01/2013
2	Tourniquets 12/2018 - 01/2013
1	Vascular Surgical Procedures 12/2018
1	Extracorporeal Membrane Oxygenation 01/2016
1	Extracorporeal Circulation 02/2014
1	Transplantation 09/2008